Leiomyosarcoma (LMS) is one of the most common subtypes of soft tissue sarcoma in adults and can occur in almost any part of the body. Uterine leiomyosarcoma is the most common subtype of uterine sarcoma. Increased awareness of this unique histology has allowed for the development of drugs that are specific to LMS and has begun to shed light on the similarities and possible unique aspects of soft tissue and uterine LMS. In this review, we summarize the current understanding of the epidemiology, diagnosis, genomics, and treatment options for LMS.

中文翻译：

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软组织和子宫平滑肌肉瘤

平滑肌肉瘤（LMS）是成人最常见的软组织肉瘤亚型之一，几乎可以发生在身体的任何部位。子宫平滑肌肉瘤是子宫肉瘤最常见的亚型。人们对这种独特组织学的认识不断提高，从而可以开发出针对 LMS 的药物，并开始揭示软组织和子宫 LMS 的相似性和可能的​​独特之处。在这篇综述中，我们总结了目前对 LMS 的流行病学、诊断、基因组学和治疗方案的理解。