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Surface modification: activation and deactivation of osteogenic differentiation based on detachable growth factor protein†
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2017-12-08 00:00:00 , DOI: 10.1039/c7tb02758c Zhen-Yu Guan,Yi-Kai Chen,Chih-Yu Wu,Shinn-Chih Wu,Jiashing Yu,Hsien-Yeh Chen
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2017-12-08 00:00:00 , DOI: 10.1039/c7tb02758c Zhen-Yu Guan,Yi-Kai Chen,Chih-Yu Wu,Shinn-Chih Wu,Jiashing Yu,Hsien-Yeh Chen
An advanced material interface is modified by using a substrate-independent coating of detachable poly-para-xylylene, enabling dynamical control of the immobilization and detachment of biomolecules, and a previously installed biological function is deactivated or tuned with reduced activity. The induction of osteogenesis activity, and subsequent deactivation of such osteogenesis activity, is demonstrated.
中文翻译:
表面修饰:基于可分离的生长因子蛋白的成骨分化的激活和失活†
通过使用可分离的聚对亚二甲苯基的独立于基材的涂层,可以改进先进的材料界面,从而可以动态控制生物分子的固定和分离,并且可以降低先前激活的生物功能或使其活性降低。证明了成骨活性的诱导以及随后这种成骨活性的失活。
更新日期:2017-12-08
中文翻译:
表面修饰:基于可分离的生长因子蛋白的成骨分化的激活和失活†
通过使用可分离的聚对亚二甲苯基的独立于基材的涂层,可以改进先进的材料界面,从而可以动态控制生物分子的固定和分离,并且可以降低先前激活的生物功能或使其活性降低。证明了成骨活性的诱导以及随后这种成骨活性的失活。