Lysine methylation is a prevalent post-translational modification (PTM) used by the cell to reversibly regulate protein function. Although it has been extensively studied in the context of histones and the associated chromatin, the remaining methyllysine proteome remains largely unexplored. This SnapShot provides an overview of the current state of lysine methylation research and its emergence as a dynamic PTM occurring on histone and non-histone proteins.

中文翻译：

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SnapShot：组蛋白之外的赖氨酸甲基化

赖氨酸甲基化是细胞普遍使用的翻译后修饰（PTM），可逆性调节蛋白质功能。尽管已经在组蛋白和相关的染色质的背景下进行了广泛的研究，但其余的甲基赖氨酸蛋白质组仍未开发。SnapShot概述了赖氨酸甲基化研究的现状，以及它作为动态PTM出现在组蛋白和非组蛋白上的概述。