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iPSC Reprogramming Is Not Just an Open and Shut Case.
Cell Stem Cell ( IF 23.9 ) Pub Date : 2017-Dec-07 , DOI: 10.1016/j.stem.2017.11.017
Peter C. Scacheri , Paul J. Tesar

What exactly happens to chromatin as cells undergo an identity change? In this issue of Cell Stem Cell, Li et al. (2017) and Knaupp et al. (2017) offer new insights by mapping in exquisite detail chromatin accessibility dynamics as mouse embryonic fibroblasts are reprogrammed into induced pluripotent stem cells.

中文翻译:

iPSC重编程不仅是一成不变的案例。

当细胞经历身份改变时,染色质究竟发生了什么?在本期的《细胞干细胞》中,Li等人。(2017)和Knaupp等人。(2017)通过绘制精美细节的染色质可及性动态图提供了新的见解,因为小鼠胚胎成纤维细胞被重新编程为诱导性多能干细胞。
更新日期:2017-12-07
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