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One flexible loop in OST lassos both substrates
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date : 2017-12-07 , DOI: 10.1038/nsmb.3508
Shiteshu Shrimal , Natalia A Cherepanova , Reid Gilmore

One flexible loop in OST lassos both substrates

One flexible loop in OST lassos both substrates, Published online: 07 December 2017; doi:10.1038/nsmb.3508

The crystal structure of an oligosaccharyltransferase in complex with a sugar donor and an acceptor peptide provides insight into the mechanism of protein glycosylation and reveals how lipid-linked oligosaccharides are positioned in the enzyme active site.


中文翻译:

OST套索中的一个灵活回路套接两个基板

OST套索中的一个灵活回路套接两个基板

OST套索在两个衬底上都存在一个灵活的回路,在线发布:2017年12月7日;doi:10.1038 / nsmb.3508

与糖供体和受体肽复合的寡糖基转移酶的晶体结构提供了对蛋白质糖基化机制的洞察力,并揭示了脂质连接的寡糖如何位于酶活性位点。
更新日期:2017-12-07
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