Mining Plants for Bacterial Quorum Sensing Modulators,ACS Chemical Biology

当前位置： X-MOL 学术 › ACS Chem. Biol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Mining Plants for Bacterial Quorum Sensing Modulators
ACS Chemical Biology ( IF 3.5 ) Pub Date : 2017-12-27 00:00:00 , DOI: 10.1021/acschembio.7b00859
Shimrit David ₁ , Aviad Mandabi ₁ , Shaked Uzi ₁ , Asaph Aharoni ₂ , Michael M. Meijler ₁

Affiliation

The bacterial plant pathogen Agrobacterium tumefaciens uses quorum sensing (QS) in order to regulate the transfer of DNA into the host plant genome, and this results in the induction of crown gall tumors. The deleterious results of these infections are widespread and affect many species of fruit and crops. In order to further our understanding of this process and to provide potential solutions, we evaluated a library of 3800 natural products from plant sources and identified potent compounds that are able to strongly modulate plant–bacterial interactions.

中文翻译：

细菌群体感应调节剂的采矿设备

细菌植物病原体根癌农杆菌使用群体感应（QS）来调节DNA向宿主植物基因组中的转移，从而导致冠状胆囊肿瘤的诱导。这些感染的有害结果广泛存在，并影响许多种类的水果和农作物。为了进一步了解该过程并提供可能的解决方案，我们评估了一个来自植物的3800种天然产物的库，并确定了能够强烈调节植物与细菌相互作用的有效化合物。

更新日期：2017-12-27

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11