Abstract We report a facile, versatile, and novel approach for the design of ultralow fouling membranes via mussel-inspired molecular functionalization and zwitterionization. Using mussel-inspired polydopamine (PDA) coatings on polysulfone microporous membranes, active molecules with tertiary amine functionality (N,N-dimethylethylenediamine (DMDA)) were grafted via Michael addition through primary amine groups. The DMDA-functionalized membrane was further reacted with 1,3-propane sultone to obtain zwitterionic membrane. The variation of surface chemistry and surface wettability upon molecular functionalization was monitored with X-ray photoelectron spectroscopy (XPS) and water contact angle measurements. Following molecular functionalization, the membranes became more hydrophilic due to strong surface hydration with PDA, and zwitterionic functional groups. The functionalized membranes showed ultralow bovine serum albumin (BSA) protein adsorption and high flux recovery after protein filtration. The versatile nature of PDA modification along with its molecular functionalization allows for the design of ultralow fouling surfaces, making this a promising membrane modification technique for water filtration and separation, but also for other antifouling applications.

中文翻译：

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用功能性聚多巴胺进行表面改性的超低污染膜

摘要 我们报告了一种通过受贻贝启发的分子功能化和两性离子化来设计超低污染膜的简便、通用和新颖的方法。在聚砜微孔膜上使用受贻贝启发的聚多巴胺 (PDA) 涂层，通过伯胺基团的迈克尔加成接枝具有叔胺官能团（N,N-二甲基乙二胺 (DMDA)）的活性分子。DMDA 功能化膜进一步与 1,3-丙烷磺内酯反应得到两性离子膜。用 X 射线光电子能谱 (XPS) 和水接触角测量监测分子官能化后表面化学和表面润湿性的变化。在分子功能化后，由于与 PDA 的强表面水合作用，膜变得更加亲水，和两性离子官能团。功能化膜显示出超低牛血清白蛋白 (BSA) 蛋白质吸附和蛋白质过滤后的高通量回收率。PDA 改性的多功能特性及其分子功能化允许设计超低污染表面，使其成为用于水过滤和分离以及其他防污应用的有前途的膜改性技术。