Abstract This review discusses basic aspects used to control the architecture and functional properties of smart hydrogels. The introduction briefly outlines what has been accomplished regarding smart hydrogels and explores historical aspects and the fundamental understanding of these systems. Then, a short discussion on the chemical interactions and the main variables involved in architectural construction is exhibited. Further analysis provides the basis for optimizing biological responses through system modulation. Finally, we outline perspectives and challenges for building smart hydrogels into functionalized and modulated delivery systems.

中文翻译：

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智能水凝胶的最新进展：从自组装到功能方法

摘要 本综述讨论了用于控制智能水凝胶结构和功能特性的基本方面。引言简要概述了智能水凝胶已取得的成就，并探讨了这些系统的历史方面和基本理解。然后，展示了对化学相互作用和建筑构造中涉及的主要变量的简短讨论。进一步的分析为通过系统调制优化生物反应提供了基础。最后，我们概述了将智能水凝胶构建成功能化和调制传递系统的前景和挑战。