The synergistic control of the S_H2 transition states of hydrogen abstraction by polar and steric effects provides a promising strategy in achieving site-selective C(sp³)–H functionalization under decatungstate anion photocatalysis. By using this photocatalytic approach, the C–H bonds of alkanes, alcohols, ethers, ketones, amides, esters, nitriles, and pyridylalkanes were functionalized site-selectively. In the remarkable case of a 2,4-disubstituted cyclohexanone bearing five methyl, five methylene, and three methine C–H bonds, one methine C–H bond in the isoamyl tether was selectively functionalized.

中文翻译：

---

十价态阴离子光催化的位点选择性C–H功能化：通过极性和立体效应的协同控制扩大了反应范围

通过极性和空间效应对氢提取的S _H 2过渡态的协同控制提供了一种有前途的策略，可在去阳离子化子阴离子光催化下实现位点选择性C（sp ³）-H功能化。通过使用这种光催化方法，对烷烃，醇，醚，酮，酰胺，酯，腈和吡啶基烷烃的C–H键进行了位点选择性官能化。在2，4-二取代的环己酮带有5个甲基，5个亚甲基和3个次甲基C–H键的显着情况下，异戊基系链中的1个次甲基C–H键被选择性官能化。