A series of triarylimidazoles substituted with 2-arylindoles (4a-4j) were prepared and evaluated for their in vitro α-Glucosidase inhibition. α-Glucosidase inhibition assay displayed a new class of highly potent agents The new compounds showed significant α-glucosidase inhibitory activity as compared to the standard inhibitor acrabose. Structures of synthesized compounds were determined by using Mass spectrometry FT-IR, ¹H NMR and ¹³C NMR.

中文翻译：

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新型咪唑衍生物与吲哚部分连接作为有效的α-葡萄糖苷酶抑制剂的生物学评估

制备了一系列被2-芳基吲哚（4a-4j）取代的三芳基咪唑，并对其体外α-葡萄糖苷酶抑制作用进行了评估。α-葡萄糖苷酶抑制测定法显示出一类新的强效剂。与标准抑制剂阿卡波糖相比，新化合物显示出显着的α-葡萄糖苷酶抑制活性。通过使用质谱FT-IR，¹ H NMR和¹³ C NMR确定合成的化合物的结构。