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RevAMPing Mitochondrial Shape to Live Longer.
Cell Metabolism ( IF 27.7 ) Pub Date : 2017-Dec-05 , DOI: 10.1016/j.cmet.2017.11.010
Lena Pernas , Luca Scorrano

Whether and how mitochondria connect reduced energy intake to healthy aging are unclear. In this issue of Cell Metabolism, Weir et al. (2017) find that constitutive AMPK activation and dietary restriction promote longevity in C. elegans via remodeling of the mitochondrial network and fatty acid oxidation in peripheral tissues.

中文翻译:

改造线粒体形状以延长寿命。

线粒体是否以及如何将减少的能量摄入与健康的衰老联系起来尚不清楚。在《细胞代谢》杂志中,Weir等人。(2017)发现组成性AMPK激活和饮食限制可通过线粒体网络重塑和周围组织中的脂肪酸氧化来促进秀丽隐杆线虫的长寿。
更新日期:2017-12-05
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