Abstract A novel synthetic strategy to afford 1,2,3-triazole grafted chitosans via modified Wolff’s cyclocondensation was established. Subsequently, several multi-substituted 1,2,3-triazole grafted chitosans with a degree of conversion (DC) varying from 42.1% to 53.9% were synthesized and characterized. The chemical structures of the modified chitosans were confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance spectroscopy (1H NMR), and the DC of chitosan derivatives were determined by amino titration. Meanwhile, the impact of 1,2,3-triazole moieties in the chitosan on their thermal properties were characterized by thermogravimetic analysis (TGA) and differential calorimetry scanner (DSC) respectively.

中文翻译：

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1,2,3-三唑接枝壳聚糖的改性沃尔夫环缩合新方法

摘要 建立了一种通过改性沃尔夫环缩合反应制备1,2,3-三唑接枝壳聚糖的新合成策略。随后，合成并表征了几种转化率 (DC) 从 42.1% 到 53.9% 不等的多取代 1,2,3-三唑接枝壳聚糖。改性壳聚糖的化学结构通过傅里叶变换红外光谱（FTIR）和质子核磁共振光谱（1H NMR）确定，壳聚糖衍生物的DC通过氨基滴定测定。同时，分别通过热重分析 (TGA) 和差示量热扫描仪 (DSC) 表征壳聚糖中的 1,2,3-三唑部分对其热性能的影响。