Front Cover: Characterization of Terminators in Saccharomyces cerevisiae and an Exploration of Factors Affecting Their Strength (ChemBioChem 24/2017),ChemBioChem

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Front Cover: Characterization of Terminators in Saccharomyces cerevisiae and an Exploration of Factors Affecting Their Strength (ChemBioChem 24/2017)
ChemBioChem ( IF 2.6 ) Pub Date : 2017-12-04 , DOI: 10.1002/cbic.201700617
Linna Wei ₁ , Zhaoxia Wang ₁ , Genlin Zhang ₁ , Bangce Ye ₁

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The front cover picture shows the transcription process in the nucleus of yeast and the translation process in the cytoplasm. The area with the blue background represents the nucleus and nucleopore on the nuclear envelope. We describe the termination principle of the yeast terminator in the nucleus: a hairpin structure (red) formed at the transcription level causes the RNA polymerase (blue ellipse) to fall off the DNA template. The green section shows the translation process of the gene in the cytoplasm. The tripolymer represents mRNA that is being translated, with the new protein emerging. The expression level of the protein can characterize the regulatory role of the yeast terminator. More information can be found in the full paper by G. Zhang et al. on page 2422 in Issue 24, 2017 (DOI: 10.1002/cbic.201700516).

中文翻译：

封面：酿酒酵母中终止子的表征以及影响其强度的因素的探索（ChemBioChem 24/2017）

封面图片显示了酵母核中的转录过程和细胞质中的翻译过程。蓝色背景区域代表核被膜上的核和核孔。我们描述了酵母终止子在细胞核中的终止原理：在转录水平上形成的发夹结构（红色）导致RNA聚合酶（蓝色椭圆形）从DNA模板上脱落。绿色部分显示了基因在细胞质中的翻译过程。三元共聚物代表了正在翻译的mRNA，并且出现了新的蛋白质。蛋白质的表达水平可以表征酵母终止子的调节作用。可以在G. Zhang等人的全文中找到更多信息。在2017年第24期的第2422页 （DOI：10.1002 / cbic.201700516）。

更新日期：2017-12-04

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