The development of catalyst based on porous crystalline materials (PCM) constructed from metal ions or clusters and multidentate organic ligands is a topic of great interest. In view of the Lewis acidic and basic properties of PCMs, we report for the first time that MIL-101(Cr) works as a synergistic catalyst for the reduction of imines with trichlorosilane as the hydrogen source. Both ketimines and aldimines were tolerated with this protocol, giving the corresponding amines in moderate to high yields. The operational simplicity as well as mild reaction conditions renders this protocol an attractive approach for the synthesis of amines. Furthermore, a chiral MOF, CMIL-101, was also realized by grafting chiral N-formyl proline derivatives to the open metal sites. Moreover, CMIL-101 exhibited a comparable catalytic performance with its homogeneous counterpart in terms of yields and enantioselectivities.

基于由金属离子或簇和多齿有机配体构成的多孔晶体材料（PCM）的催化剂的开发是非常感兴趣的主题。鉴于PCM的Lewis酸性和碱性，我们首次报道MIL-101（Cr）作为三氯硅烷为氢源还原亚胺的协同催化剂。此方案可耐受酮亚胺和醛亚胺，从而以中等至高收率得到相应的胺。操作简便以及反应条件温和，使该方案成为合成胺的有吸引力的方法。此外，还通过接枝手性N实现了手性MOF CMIL-101-甲酰基脯氨酸衍生物的开放金属位点。此外，就产率和对映选择性而言，CMIL-101表现出与同类均相催化剂相当的催化性能。