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Enzymatic chemical transformations of aldehydes, ketones, esters and alcohols using plant fragments as the only biocatalyst: Ximenia americana grains
Molecular Catalysis ( IF 3.9 ) Pub Date : 2017-12-01 , DOI: 10.1016/j.mcat.2017.11.033
Romézio Alves Carvalho da Silva , Bruna Marques de Mesquita , Iolanda Frota de Farias , Patrícia Georgiana Garcia do Nascimento , Telma Leda Gomes de Lemos , Francisco José Queiroz Monte

The present study demonstrated the ability of Ximenia american as a biocatalyst in reduction, hydrolysis and esterification reactions. The reduction reactions of aldehydes and ketones, ester hydrolysis and esterification of alcohols were carried out with interesting results. Reduction of ketones afforded yields of 6–60% with ee in the range of 35–>99% and that of aldehydes in yields of 51–99%. On the other hand, ester hydrolysis afforded yields of 58–98% with ee in the range 34–87%, while esterification of alcohols in 18–99% yields. Experimental conditions for all reactions have been defined using standard substrates as indicated in results and discussion. Some of the products are the potential building blocks for the synthesis of molecules which are of pharmaceutical and agrochemical importance.



中文翻译:

的醛,酮,酯酶的化学转化和使用植物的片段作为唯一的生物催化剂的醇:海檀木晶粒

本研究证明了西美尼亚作为还原,水解和酯化反应的生物催化剂的能力。进行了醛和酮的还原反应,醇的酯水解和酯化反应,得到了有趣的结果。还原酮可得到6-60%的收率,ee在35-> 99%的范围内,醛的收率在51-99%的范围内。另一方面,使用ee进行酯水解可得到58-98%的收率醇的酯化率在34%至87%之间,而酯化率在18%至99%之间。如结果和讨论所示,已使用标准底物定义了所有反应的实验条件。一些产品是合成具有药物和农用化学重要性的分子的潜在组成部分。

更新日期:2017-12-01
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