MRI-guided focused ultrasound is a novel method for creating thermic ablations in the thalamus or basal ganglia without opening the skull. The method uses focused sonic energy and real-time MRI thermography of brain temperature to control lesion size and location precisely. This is a principle advantage over gamma-knife radiosurgery, which is another incision-free lesioning technique but induces radionecrosis that is difficult to control and develops within months of the procedure. In July, 2016, the US Food and Drug Administration approved MRI-guided focused ultrasound for unilateral thalamotomy for treatment of medically refractory and disabling essential tremor.

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帕金森氏病的丘脑下疗法：回到未来？

MRI引导的聚焦超声是一种在不打开颅骨的情况下在丘脑或基底神经节中产生热消融的新方法。该方法利用聚焦的声能和实时的脑部温度MRI热像仪来精确控制病变的大小和位置。这是优于伽马刀放射外科的主要优点，伽马刀放射外科是另一种无切口的损伤技术，但是会诱发放射性坏死，该坏死难以控制并且在手术后的几个月内会发展。2016年7月，美国食品药品监督管理局批准了MRI引导的聚焦超声用于单侧丘脑切开术，以治疗难治性和致残性原发性震颤。