Fast pyrolysis followed by catalytic hydroconversion is a value chain aimed to transform lignocellulosic biomass into biofuel or chemicals. During hydroconversion, desired catalytic deoxygenation reactions are in competition with thermal side reactions like condensation or oligomerization. These undesired pathways lead to high molecular weight compounds (i.e. macromolecules) that are responsible for catalyst deactivation and severe plugging of the reactor. We investigate here the impact of a phenolic compound on the formation of these macromolecules. Catalytic hydroconversion of a fast pyrolysis bio-oil and a bio-oil/guaiacol (50/50 wt%) mixture were carried out in a batch reactor using a NiMo/alumina catalyst. An extended analytical strategy has been developed involving size-exclusion chromatography (SEC) and liquid state ¹³C NMR dedicated to the in depth characterization of effluents as well as physicochemical analysis of the fresh and used catalyst (XRD, Hg porosimetry, N₂ physisorption, STEM). This strategy allowed bringing new insights on aromatic structures larger than 1000 g.mol⁻¹ and their formation mechanism. This formation can be chemically inhibited by the introduction of organic component such as guaiacol. This stabilization was mainly observed and explained at low temperature and short reaction time.

快速热解后再进行催化加氢转化是旨在将木质纤维素生物质转化为生物燃料或化学物质的价值链。在加氢转化过程中，所需的催化脱氧反应与热副反应（如缩合或低聚）竞争。这些不希望的途径导致负责催化剂失活和反应器严重堵塞的高分子量化合物（即大分子）。我们在这里研究酚类化合物对这些大分子形成的影响。快速热解生物油和生物油/愈创木酚（50/50 wt％）混合物的催化加氢转化是在使用NiMo /氧化铝催化剂的间歇式反应器中进行的。已开发出一种扩展的分析策略，涉及尺寸排阻色谱法（SEC）和液态¹³ C NMR专门用于废水的深度表征以及新鲜和使用过的催化剂的物理化学分析（XRD，Hg孔隙率法，N ₂物理吸附，STEM）。该策略允许对大于1000 g.mol ^-1的芳族结构及其形成机理带来新的见解。可以通过引入有机成分（例如愈创木酚）来化学抑制这种形成。主要在低温和短反应时间下观察到并说明了这种稳定作用。