Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism,Chemical Communications

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Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism
Chemical Communications ( IF 4.3 ) Pub Date : 2017-11-29 00:00:00 , DOI: 10.1039/c7cc08820e
Jiaheng Sun _{1,

2,

3,

4,

5} , Qi Xin _{3,

4,

5,

6} , Yang Yang _{3,

4,

5,

6} , Hameed Shah _{3,

4,

5,

6} , Hongqian Cao _{1,

2,

3,

4,

5} , Yanfei Qi _{1,

2,

3} , Jian Ru Gong _{3,

4,

5,

6} , Junbai Li _{6,

7,

8,

9,

10}

Affiliation

A novel material with a large two-photon absorption cross-section was conjugated with a typical photosensitizer for inducing a FRET process. The photosensitizer can be excited by a one-/two-photon laser and then induced photo-toxicity in vitro and in vivo. The system presents great potential for improving treatment depth and the precision of traditional photodynamic therapy.

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