A new analysis of cancer genomes identifies a decrease in the mutation burden of exons, but not introns, as compared to expectation. This difference can be explained by preferential recruitment of the DNA mismatch repair machinery to a protein modification that marks exons.

中文翻译：

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错配修复更喜欢外显子。

对癌症基因组的新分析表明，与预期相比，外显子（而非内含子）的突变负担减少了。可以通过将DNA错配修复机制优先招募到标记外显子的蛋白质修饰来解释这种差异。