Steroidal alkaloids (SAs) are widely synthesized and distributed in plants manifesting as natural produce endowed with potential for medicinal, pesticidal and other high-value usages. Glycosylation of these SAs raises complex and diverse glycosides in plant cells that indeed govern numerous functional aspects. During the glycosylation process of these valuable metabolites, the addition of carbohydrate molecule(s) is catalyzed by enzymes known as sterol glycosyltransferases (SGTs), commonly referred to as UGTs, leading to the production of steryl glycosides (SGs). The ratio of SGs and nonglyco-conjugated SAs are different in different plant species, however, their biosynthesis in the cell is controlled by different environmental factors. The aim of this review is to evaluate the current SGT enzyme research and the functional consequences of glycomodification of SAs on the physiology and plant development, which together are associated with the plant's primary processes. Pharmaceutical, industrial, and other potential uses of saponins have also been discussed and their use in therapeutics has been unveiled by in silico analysis. The field of biotransformation or conversion of nonglycosylated to glycosylated phytosterols by the activity of SGTs, making them soluble, available and more useful for humankind is the new field of interest towards drug therapy.

甾体生物碱（SAs）广泛合成并分布在植物中，表现为天然产物，具有药用，杀虫和其他高价值用途的潜力。这些SA的糖基化在植物细胞中产生复杂而多样的糖苷，这些糖苷确实控制着许多功能方面。在这些有价值的代谢物的糖基化过程中，碳水化合物分子的添加被称为固醇糖基转移酶（SGT）（通常称为UGT）的酶催化，从而导致生成固醇糖苷（SGs）。SG和非糖基SA的比例在不同的植物物种中是不同的，但是，它们在细胞中的生物合成受不同的环境因素控制。这篇综述的目的是评估当前的SGT酶研究以及SA的糖基修饰对生理和植物发育的功能后果，这些后果与植物的主要过程相关。还讨论了皂苷在制药，工业和其他方面的潜在用途，并公开了其在治疗中的用途。在计算机分析中。通过SGT的活性将非糖基化植物甾醇进行生物转化或转化的领域，使它们可溶，可利用且对人类更有用，这是药物治疗的新领域。