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Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks
Nature Cell Biology ( IF 21.3 ) Pub Date : 2017-11-27 , DOI: 10.1038/ncb3643 Flavia Michelini , Sethuramasundaram Pitchiaya , Valerio Vitelli , Sheetal Sharma , Ubaldo Gioia , Fabio Pessina , Matteo Cabrini , Yejun Wang , Ilaria Capozzo , Fabio Iannelli , Valentina Matti , Sofia Francia , G. V. Shivashankar , Nils G. Walter , Fabrizio d’Adda di Fagagna
Nature Cell Biology ( IF 21.3 ) Pub Date : 2017-11-27 , DOI: 10.1038/ncb3643 Flavia Michelini , Sethuramasundaram Pitchiaya , Valerio Vitelli , Sheetal Sharma , Ubaldo Gioia , Fabio Pessina , Matteo Cabrini , Yejun Wang , Ilaria Capozzo , Fabio Iannelli , Valentina Matti , Sofia Francia , G. V. Shivashankar , Nils G. Walter , Fabrizio d’Adda di Fagagna
Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks
中文翻译：
损伤诱导的lncRNA通过在单个双链断裂处与DDRNA相互作用来控制DNA损伤反应。
损伤诱导的lncRNA通过在单个双链断裂处与DDRNA相互作用来控制DNA损伤反应。
更新日期：2017-11-28
Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks, Published online: 27 November 2017; doi:10.1038/ncb3643
Michelini et al. show that RNA polymerase II is recruited to double-strand breaks to induce long non-coding RNAs and the generation of small DNA damage response RNAs that promote recruitment of DNA repair factors and repair.中文翻译：
损伤诱导的lncRNA通过在单个双链断裂处与DDRNA相互作用来控制DNA损伤反应。
损伤诱导的lncRNA通过在单个双链断裂处与DDRNA相互作用来控制DNA损伤反应。
损伤诱导的lncRNA通过在单个双链断裂处与DDRNA相互作用来控制DNA损伤反应，在线发布：2017年11月27日；doi：10.1038 / ncb3643
Michelini等。结果表明，RNA聚合酶II被募集到双链断裂，以诱导长的非编码RNA和小DNA损伤反应RNA的产生，从而促进了DNA修复因子的募集和修复。
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