Virtual screening was performed against a homology model of Chlamydia trachomatis type III secretion system (T3SS) ATPase. As a result, a series of N-arylbenzylamines was identified as compounds that were able to inhibit effector protein export by C. trachomatis T3SS and suppress chlamydial development inside eukaryotic cells.

中文翻译：

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通过针对T3SS ATPase的虚拟筛选鉴定衣原体T3SS抑制剂

针对沙眼衣原体III型分泌系统（T3SS）ATPase的同源性模型进行了虚拟筛选。结果，一系列N-芳基苄胺被鉴定为能够抑制沙眼衣原体T3SS输出效应蛋白并抑制真核细胞内衣原体发育的化合物。