This paper reports the results of the synthesis and structural elucidation by multinuclear NMR spectroscopy and single crystal X-ray diffraction of a new series of four examples of 1,1-difluoro-3-methyl-9-(aryl/heteroaryl)-7-(trifluoromethyl)-1H-[1,3,5,2]oxadiazaborinino[3,4-a][1,8]naphthyridin-11-ium-1-uides, which were obtained, at good yields (60–66%), from the reaction of 7-substituted N-(5-(trifluoromethyl)-1,8-naphthyridin-2-yl)acetamides — in which the 7-substituents are C₆H₅, 4-CH₃C₆H₄, 4-FC₆H₄, and 2-Thienyl — with BF₃·Et₂O solution. One-dimensional multinuclear NMR spectroscopy (¹H, ¹³C, ¹⁹F, and ¹¹B) and two-dimensional ¹H–¹⁵N HMBC are presented as powerful tools for an easy and secure NMR chemical shift assignments and structural characterization of fluorinated 1,8-naphthyridine-based boron complexes. Additionally, investigations of photophysical, electrochemical and DNA-binding properties were done.

本文通过多核NMR光谱和单晶X射线衍射报告了一系列新的1,1-二氟-3-甲基-9-（芳基/杂芳基）-7-的四个实例的合成和结构解析结果。 （三氟甲基）-1 H- [1,3,5,2]恶二氮杂硼酸酯[3,4- a ] [1,8]萘啶11 -1--1-铀，收率良好（60-66 ％），由7个取代的N-（5-（三氟甲基）-1,8-萘啶-2-基）乙酰胺的反应制得，其中7个取代基为C ₆ H _5，4 -CH ₃ C ₆ H _4，4 -FC ₆ H ₄和2-噻吩基-BF ₃ · Et₂ O溶液。一维多核NMR光谱（¹ H，¹³ C，¹⁹ F和¹¹ B）和二维¹ H– ¹⁵ N HMBC被认为是强大而有效的工具，可轻松，安全地进行NMR化学位移分配和氟化1的结构表征。 ，8-萘啶基硼配合物。此外，还进行了光物理，电化学和DNA结合特性的研究。