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Toward nucleophilic trifluoroethylation: Generation, stabilization and alkylation of 1-substituted and 1,1-disubstituted 2,2,2-trifluoroethyl carbanion equivalents
Journal of Fluorine Chemistry ( IF 1.9 ) Pub Date : 2017-07-31 , DOI: 10.1016/j.jfluchem.2017.07.010
Kenji Uneyama , Takashi Yamazaki

Introduction of fluorine atoms or fluorine-containing groups are recognized as one of the extremely important methods for endowing special properties due to this specific atoms, and thus, a variety of protocols have been devised thus far. This review article deals with the 2,2,2-trifluoroethylated carbanionic species with possible halogen atoms at the 1 position whose generation, stability, and utility are described from their experimental as well as computational viewpoint.



中文翻译:

亲核三氟乙基化:1-取代和1,1-二取代的2,2,2-三氟乙基碳负离子当量的产生,稳定化和烷基化

由于该特定原子,引入氟原子或含氟基团被认为是赋予特殊性质的极其重要的方法之一,因此,迄今为止已经设计了多种方案。这篇综述文章涉及在1位可能带有卤素原子的2,2,2-三氟乙基化碳负离子物质,从其实验和计算的角度描述了其生成,稳定性和实用性。

更新日期:2017-07-31
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