We report on the rate of reduction of a popular electrophilic trifluoromethylating agent, Togni’s reagent (T-CF₃), with solvated electrons (e_aq⁻) generated by pulse radiolysis. By means of competition experiments against methyl viologen (MV²⁺) and direct observation of the decay of e_aq⁻ we determined k(T-CF₃ + e_aq⁻) ≈ 2 × 10¹⁰ M⁻¹ s⁻¹. To the best of our knowledge, this constitutes the first report on a reduction of T-CF₃ with an unambiguously clear outer-sphere mechanism. Furthermore, we studied the oxidation of 2-(2-iodophenyl)propan-2-ol (ROH) by peroxyl-radicals to a presumably cyclic iodanyl radical RI. This species RI was not detected during the reduction of T-CF₃ with e_aq⁻ and therefore, this reduction does not proceed via heterolytic I-CF₃ bond cleavage to CF₃⁻ and RI. More likely, a CF₃ radical is formed, as was observed in numerous synthesis studies reported to date.

我们关于减少一个流行的电子三氟甲基化剂的速率报告，TOGNI试剂（T-CF ₃）中，用溶剂化电子（e_水溶液^- ）通过脉冲辐解生成。通过针对甲基紫精（MV竞争实验手段²⁺）和电子衰减的直接观察_水溶液^-我们确定ķ（T-CF ₃  + E_水溶液^-）≈2×10 ¹⁰中号^-1小号^-1。据我们所知，这是关于T-CF ₃还原的第一个报告，其外部明确无误球机制。此外，我们研究了过氧自由基将2-（2-碘苯基）丙-2-醇（ROH）氧化为大概环状的碘丹基RI 。这一物种RI T-CF的还原过程中未检测到₃随e_水溶液^-并且因此，这种降低不经由异裂I-CF继续进行₃键断裂以CF ₃ ^-和RI 。如迄今为止报道的许多合成研究中所观察到的，形成CF ₃自由基的可能性更大。