Medullary thymic epithelial cells (mTECs) play a central role in T cell tolerance. However, how the mTEC compartment is maintained remains elusive. We review recent discoveries on new transcription factors involved in mTEC homeostasis and discuss the possibility that their actions might be facilitated by the unique biology of mTECs.

中文翻译：

---

设置公差范围：深入了解mTEC生理学

髓样胸腺上皮细胞（mTECs）在T细胞耐受性中起着核心作用。但是，如何保持mTEC隔间仍然难以捉摸。我们回顾了有关mTEC稳态的新转录因子的最新发现，并讨论了mTECs独特的生物学可能促进其作用的可能性。