Synthesis ( IF 2.2 ) Pub Date : 2017-11-23 , DOI: 10.1055/s-0036-1591730 Miguel Vázquez 1 , Fernando Hernández-Borja 1 , Leticia Contreras 1 , Julio López 1 , Yolanda Alcaraz 2 , David Cruz 1 , Samuel Estrada-Soto 3 , Francisco Delgado 4
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Abstract
In this study, a molecular hybridization strategy was used to design and synthesize two novel series of hybrid compounds: 4H-pyran-lipoic and 4H-pyran-azetidine, employing ammonium hydroxide and involving the participation of aldehydes, malononitrile, and compounds derived from β-ketoesters to obtain the products with good yields.
In this study, a molecular hybridization strategy was used to design and synthesize two novel series of hybrid compounds: 4H-pyran-lipoic and 4H-pyran-azetidine, employing ammonium hydroxide and involving the participation of aldehydes, malononitrile, and compounds derived from β-ketoesters to obtain the products with good yields.
中文翻译：
新型杂化4H-吡喃-硫辛酸和4H-吡喃-氮杂环丁烷衍生物的合成
摘要
在这项研究中，使用分子杂交策略设计和合成了两个新颖的杂化化合物系列：4 H-吡喃硫辛酸和4 H-吡喃氮杂环丁烷，使用氢氧化铵并涉及醛，丙二腈和衍生的化合物的参与从β-酮酸酯中获得具有良好收率的产物。
在这项研究中，使用分子杂交策略设计和合成了两个新颖的杂化化合物系列：4 H-吡喃硫辛酸和4 H-吡喃氮杂环丁烷，使用氢氧化铵并涉及醛，丙二腈和衍生的化合物的参与从β-酮酸酯中获得具有良好收率的产物。
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