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Potassium Carbonate Promoted C–N Coupling Reaction between Benzamides and Aryl Iodides
Synthesis ( IF 2.2 ) Pub Date : 2017-11-23 , DOI: 10.1055/s-0036-1591843
Songlin Zhang , Fei Huang , San Wu , Weiye Hu

Abstract

A practical and efficient method for N-arylation of benz­amides promoted by potassium carbonate in the presence of DMEDA was developed. The reaction was carried out without addition of any transition-metal catalyst to afford a variety of N-arylated products in moderate to good yields (up to 97%).

A practical and efficient method for N-arylation of benz­amides promoted by potassium carbonate in the presence of DMEDA was developed. The reaction was carried out without addition of any transition-metal catalyst to afford a variety of N-arylated products in moderate to good yields (up to 97%).



中文翻译:

碳酸钾促进苯甲酰胺和碘代碘化物之间的CN偶联反应

摘要

开发了一种在DMEDA存在下碳酸钾促进的苯甲酰胺N-芳基化的实用有效方法。该反应在不添加任何过渡金属催化剂的情况下进行,以中等至良好的产率(高达97%)提供了多种N-芳基化产物。

开发了一种在DMEDA存在下碳酸钾促进的苯甲酰胺N-芳基化的实用有效方法。该反应在不添加任何过渡金属催化剂的情况下进行,以中等至良好的产率(高达97%)提供了多种N-芳基化产物。

更新日期:2017-11-23
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