Bicyclo[1.1.1]pentane-Derived Building Blocks for Click Chemistry,European Journal of Organic Chemistry

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Bicyclo[1.1.1]pentane-Derived Building Blocks for Click Chemistry
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2017-11-23 02:12:04 , DOI: 10.1002/ejoc.201701296
Serhii O. Kokhan _{1,

2} , Yevheniia B. Valter ₂ , Andriy V. Tymtsunik _{2,

3} , Igor V. Komarov _{1,

2} , Oleksandr O. Grygorenko _{1,

2}

Affiliation

Syntheses of mono- and bifunctional bicyclo[1.1.1]pentane-derived azides and terminal alkynes – promising building blocks for medicinal, combinatorial, and bioconjugate chemistry – are described. The utility of the title products as substrates for copper-catalysed click reactions is also demonstrated.

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