A simple technique to design microfluidic devices for system integration,Analytical Methods

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A simple technique to design microfluidic devices for system integration
Analytical Methods ( IF 2.7 ) Pub Date : 2017-10-16 00:00:00 , DOI: 10.1039/c7ay02177a
Mimi X. Yang _{1,

2,

3,

4} , Benjamin Wang _{2,

3,

4,

5} , Xiaolin Hu _{1,

2,

3,

4} , H.-S. Philip Wong _{1,

2,

3,

4}

Affiliation

We present a robust method to fabricate a polydimethylsiloxane (PDMS) microfluidic device with critical channel features located near the periphery. The fabricated device has a window cutout, allowing close placement and integration of the channel with solid state circuits and devices. The flow characteristics of the fabricated device are shown to closely follow that of theoretical behavior, making it an appropriate alternative to a monolithic, cast-molded device. As an illustration of the use of this method, a novel integrated microfluidic-electronic system is demonstrated with the microfluidic channel bonded directly onto the surface of an integrated circuit while leaving access to probe pads on the chip's surface. This fabrication process has important implications in furthering the development of next generation microfluidic-based lab on chip systems.

中文翻译：

设计用于系统集成的微流控设备的简单技术

我们提出了一种健壮的方法来制造具有位于周边附近的关键通道特征的聚二甲基硅氧烷（PDMS）微流体装置。所制造的器件具有窗口切口，从而可以将通道与固态电路和器件紧密放置并集成在一起。所制造的装置的流动特性显示出紧密遵循理论行为的特性，使其成为整体铸造成型装置的合适替代品。作为使用此方法的说明，展示了一种新颖的集成微流体电子系统，该微流体通道直接键合到集成电路的表面，同时保留了访问芯片表面探针的通道。

更新日期：2017-11-23

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