The 2015 Nobel Prize in Medicine was shared in part by the discoverers of ivermectin.1 Donated tablets of ivermectin have been distributed in Africa since 1988 through mass drug administration programs for onchocerciasis, or river blindness (caused by Onchocerca volvulus),2 and since 2000 for lymphatic filariasis (caused by Wuchereria bancrofti).3 These vectorborne filarial parasites cause disabling and stigmatizing diseases, especially in impoverished populations. The complex lifecycles of these parasites include male and female adult worm stages, in which fertilized females in humans release microfilariae that can be ingested by simulium black flies from the skin, in the case of onchocerciasis, . . .

中文翻译：

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伊凡菌素在Loa loa流行地区的大规模管理

伊维菌素的发现者部分分享了2015年诺贝尔医学奖.1自1988年以来，捐赠的伊维菌素片剂通过针对盘尾丝虫病或河盲症（由盘尾丝虫引起的）的大规模药物管理计划在非洲分发，2自2000年以来3这些媒介传播的丝虫寄生虫会造成致残性疾病和污名化疾病，特别是在贫困人口中。这些寄生虫的复杂生命周期包括成虫和成虫的成虫阶段，在人类中，受精的雌性会释放微丝虫病，在盘尾丝虫病的情况下，类似的黑蝇会从皮肤中摄取这些丝虫病。。。