Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions,Chemical Communications

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Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions
Chemical Communications ( IF 4.3 ) Pub Date : 2017-11-22 00:00:00 , DOI: 10.1039/c7cc07038a
Rachael A. Day _{1,

2,

3,

3,

4} , Daniel A. Estabrook _{1,

2,

3,

3,

4} , Jessica K. Logan _{1,

2,

3,

3,

4} , Ellen M. Sletten _{1,

2,

3,

3,

4}

Affiliation

Photodynamic therapy (PDT) requires a photosensitizer, light, and oxygen to induce cell death. The majority of efforts to advance PDT focus only on the first two components. Here, we employ perfluorocarbon nanoemulsions to simultaneously deliver oxygen and a photosensitizer. We find that the implementation of fluorous soluble photosensitizers enhances the efficacy of PDT.

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