Continuous multi-step synthesis by extrusion – telescoping solvent-free reactions for greater efficiency,Chemical Communications

当前位置： X-MOL 学术 › Chem. Commun. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Continuous multi-step synthesis by extrusion – telescoping solvent-free reactions for greater efficiency
Chemical Communications ( IF 4.3 ) Pub Date : 2017-11-10 00:00:00 , DOI: 10.1039/c7cc06010f
Deborah E. Crawford _{1,

2} , Clodagh K. Miskimmin _{1,

2} , John Cahir _{1,

2} , S. L. James _{1,

2}

Affiliation

Chemical manufacturing typically requires more than one step, involving multiple batch processes, which makes synthesis at scale laborious and wasteful. Herein, we demonstrate that several reactions can be telescoped into a single continuous process and/or be carried out as a continuous multi-component reaction (MCR), by twin screw extrusion (TSE), in the complete absence of solvent.

中文翻译：