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The TCR Takes Some Immune Responsibility
Immunity ( IF 25.5 ) Pub Date : 2017-11-21 , DOI: 10.1016/j.immuni.2017.10.018 Ashley A Viehmann Milam 1 , Paul M Allen 1
中文翻译：
TCR 承担一些免疫责任
更新日期：2017-11-21
Immunity ( IF 25.5 ) Pub Date : 2017-11-21 , DOI: 10.1016/j.immuni.2017.10.018 Ashley A Viehmann Milam 1 , Paul M Allen 1
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In this issue of Immunity, Van Braeckel-Budimir et al. (2017) reveal that the pathogenic response of mice to a Plasmodium berghei infection is dominated by a Vβ8.1 T cell response. Mice lacking Vβ8.1 T cells fail to mount a pathogenic response, thus showing that the TCR locus can be an Immune response (Ir) gene.
中文翻译：
TCR 承担一些免疫责任
在本期《免疫》中，Van Braeckel-Budimir 等人。(2017) 揭示小鼠对伯氏疟原虫感染的致病反应主要是 Vβ8.1 T 细胞反应。缺乏 Vβ8.1 T 细胞的小鼠无法产生致病反应，从而表明 TCR 基因座可能是免疫反应 ( Ir ) 基因。
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