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The Silent Undertakers: Macrophages Programmed for Efferocytosis
Immunity ( IF 25.5 ) Pub Date : 2017-11-21 , DOI: 10.1016/j.immuni.2017.10.010
Judith E. Allen , Dominik Rückerl

Two recent Immunity papers provide new insight into efferocytosis by tissue-resident macrophages. Baratin et al. (2017) identify a resident macrophage population in the T cell zone of lymph nodes responsible for the silent uptake of vast numbers of apoptotic cells. Roberts et al. (2017) find that resident macrophages can be programmed by local tissue signals not to respond to the nucleic acid of apoptotic cells.



中文翻译:

沉默者:巨噬细胞编程的泡腾

最近的两篇Immunity论文为组织驻留巨噬细胞的胞吞作用提供了新的见解。Baratin等。(2017)在淋巴结的T细胞区确定了一个常驻巨噬细胞种群,负责大量凋亡细胞的无声摄取。罗伯茨等。(2017)发现常驻巨噬细胞可以通过局部组织信号进行编程,以不对凋亡细胞的核酸做出反应。

更新日期:2017-11-21
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