BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment,Journal of the National Cancer Institute

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BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment
Journal of the National Cancer Institute ( IF 10.3 ) Pub Date : 2017-11-18 , DOI: 10.1093/jnci/djx227
Yueye Huang _{1,

2} , Shen Qu ₂ , Guangwu Zhu ₁ , Fei Wang ₁ , Rengyun Liu ₁ , Xiaopei Shen ₁ , David Viola ₃ , Rossella Elisei ₃ , Efisio Puxeddu ₄ , Laura Fugazzola ₅ , Carla Colombo ₅ , Barbara Jarzab ₆ , Agnieszka Czarniecka ₆ , Alfred K Lam ₇ , Caterina Mian ₈ , Federica Vianello ₉ , Linwah Yip ₁₀ , Garcilaso Riesco-Eizaguirre _{11,

12,

13} , Pilar Santisteban _{12,

13} , Christine J O’Neill ₁₄ , Mark S Sywak ₁₄ , Roderick Clifton-Bligh ₁₄ , Bela Bendlova ₁₅ , Vlasta Sýkorová ₁₅ , Mingzhao Xing ₁

Affiliation

Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
Department of Endocrinology and Metabolism and the Shanghai Research Center of Thyroid Diseases, The Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
Endocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
Department of Internal Medicine, University of Perugia, Perugia, Italy
Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, and Department of Pathophysiology and Transplantation, University of Milan, Milan Italy
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland
Cancer Molecular Pathology of School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia
Department of Medicine, Endocrinology Unit, University of Padua, Padua, Italy
Veneto Institute of Oncology, IRCCS, Padua, Italy
University of Pittsburgh School of Medicine, Pittsburgh, PA
Department of Endocrinology and Nutrition Hospital Universitario La Paz and Hospital, Universitario de Mostoles, 28029 Madrid, Spain
Biomedical Research Institute “Alberto Sols,” Consejo Superior de Investigaciones Cientificas and Universidad Autonoma de Madrid, 28029 Madrid, Spain
Ciberonc, Health Institute Carlos III, 28029 Madrid, Spain
Endocrine Surgical Unit, The University of Sydney, Sydney, Australia
Department of Molecular Endocrinology Institute of Endocrinology, Prague, Czech Republic

Precise risk stratification-based treatment of solitary intrathyroidal papillary thyroid cancer (SI-PTC) that is larger than 1.0 cm and 4.0 cm or less is undefined.

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