Two recent studies show that incomplete repair of DNA damage due to oxidized nucleotides is crucial for reactive oxygen species (ROS)-related antimicrobial lethality. Using widely different experimental approaches they both reach the same conclusions on the role of downstream ROS production in cell killing upon exposure to bactericidal antimicrobials.

中文翻译：

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通过不完全的DNA修复杀死抗生素

最近的两项研究表明，由于氧化核苷酸造成的DNA损伤的不完全修复对于与活性氧（ROS）相关的抗菌杀伤力至关重要。通过使用广泛不同的实验方法，当暴露于杀菌剂后，下游ROS产生在细胞杀伤中的作用都得出了相同的结论。