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Risky Business: The Circuits that Impact Stress-Induced Decision-Making.
Cell ( IF 45.5 ) Pub Date : 2017-Nov-16 , DOI: 10.1016/j.cell.2017.11.004
Amy F.T. Arnsten , Daeyeol Lee , Christopher Pittenger

How does stress promote risky decision-making? Friedman et al. find that stress disrupts inhibition of striatal circuits by prefrontal cortex, rendering animals insensitive to potential losses. This may help explain how stress contributes to substance abuse and how it can disinhibit automatic behaviors, such as tics in Tourette syndrome.

中文翻译:

风险业务:影响压力诱导的决策制定的电路。

压力如何促进风险决策?弗里德曼(Friedman)等人。发现压力破坏了前额叶皮层对纹状体回路的抑制,使动物对潜在损失不敏感。这可能有助于解释压力如何导致药物滥用以及如何抑制自动行为,例如抽动秽语综合症中的抽动。
更新日期:2017-11-19
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