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Palladium-Catalyzed Safe Cyanation of Aryl Iodides with Hexamethylenetetramine
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2017-11-15 00:00:00 , DOI: 10.1021/acs.joc.7b02373
Yunjing Yan 1 , Song Sun 1 , Jiang Cheng 1
Affiliation  

A palladium-catalyzed cyanation of aryl halides with hexamethylenetetramine as a safe cyanide source is achieved, providing aromatic nitriles in moderate to good yields. This approach shows good functional group compatibilities and avoids the use of toxic cyanide source.

中文翻译:

钯催化的六亚甲基四胺氰基芳基化物的安全氰化

使用六亚甲基四胺作为安全的氰化物源,实现了钯催化的芳基卤化物的氰化氰化物,从而以中等至良好的收率提供了芳族腈。这种方法显示出良好的官能团相容性,并且避免使用有毒的氰化物源。
更新日期:2017-11-16
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