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PRGdb 3.0: a comprehensive platform for prediction and analysis of plant disease resistance genes
Nucleic Acids Research ( IF 14.9 ) Pub Date : 2017-11-16 , DOI: 10.1093/nar/gkx1119
Cristina M Osuna-Cruz , Andreu Paytuvi-Gallart , Antimo Di Donato , Vicky Sundesha , Giuseppe Andolfo , Riccardo Aiese Cigliano , Walter Sanseverino , Maria R Ercolano

The Plant Resistance Genes database (PRGdb; http://prgdb.org) has been redesigned with a new user interface, new sections, new tools and new data for genetic improvement, allowing easy access not only to the plant science research community but also to breeders who want to improve plant disease resistance. The home page offers an overview of easy-to-read search boxes that streamline data queries and directly show plant species for which data from candidate or cloned genes have been collected. Bulk data files and curated resistance gene annotations are made available for each plant species hosted. The new Gene Model view offers detailed information on each cloned resistance gene structure to highlight shared attributes with other genes. PRGdb 3.0 offers 153 reference resistance genes and 177 072 annotated candidate Pathogen Receptor Genes (PRGs). Compared to the previous release, the number of putative genes has been increased from 106 to 177 K from 76 sequenced Viridiplantae and algae genomes. The DRAGO 2 tool, which automatically annotates and predicts (PRGs) from DNA and amino acid with high accuracy and sensitivity, has been added. BLAST search has been implemented to offer users the opportunity to annotate and compare their own sequences. The improved section on plant diseases displays useful information linked to genes and genomes to connect complementary data and better address specific needs. Through, a revised and enlarged collection of data, the development of new tools and a renewed portal, PRGdb 3.0 engages the plant science community in developing a consensus plan to improve knowledge and strategies to fight diseases that afflict main crops and other plants.

中文翻译:

PRGdb 3.0:用于植物抗病基因预测和分析的综合平台

植物抗性基因数据库(PRGdb; http://prgdb.org)已经过重新设计,具有新的用户界面,新的部分,新的工具和用于遗传改良的新数据,不仅使植物科学研究界以及想要提高植物抗病性的育种者都能轻松访问。主页提供了易于阅读的搜索框的概述,这些搜索框可简化数据查询并直接显示已从候选基因或克隆基因中收集数据的植物物种。批量数据文件和精选的抗性基因注释可用于托管的每种植物。新的“基因模型”视图提供了有关每个克隆的抗性基因结构的详细信息,以突出显示与其他基因的共享属性。PRGdb 3.0提供了153个参考抗性基因和177072个带注释的候选病原体受体基因(PRG)。与以前的版本相比,rid科和藻类基因组。添加了DRAGO 2工具,该工具可以高度准确和灵敏地从DNA和氨基酸自动注释和预测(PRG)。BLAST搜索已实现,以为用户提供注释和比较他们自己的序列的机会。关于植物病害的改进部分显示了与基因和基因组相关的有用信息,以连接互补数据并更好地满足特定需求。通过修订和扩大的数据收集,新工具的开发以及门户的更新,PRGdb 3.0促使植物科学界制定了一项共识计划,以提高知识和战略来抗击侵害主要农作物和其他植物的疾病。
更新日期:2018-01-05
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