Phosphorylation-type (P-type) ATPases are ubiquitous primary transporters that pump cations across cell membranes through the formation and breakdown of a phosphoenzyme intermediate. Structural investigations suggest that the transport mechanism is defined by conformational changes in the cytoplasmic domains of the protein that are allosterically coupled

中文翻译：

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单分子FRET揭示P型ATP酶运输的动力学。

磷酸化型（P型）ATPase是普遍存在的一级转运蛋白，通过磷酸酶中间体的形成和分解将阳离子泵过细胞膜。结构研究表明，转运机制是由变构偶联的蛋白质胞质结构域的构象变化决定的