当前位置: X-MOL 学术Neuron › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A Synaptic Basis for GLP-1 Action in the Brain.
Neuron ( IF 14.7 ) Pub Date : 2017-Nov-15 , DOI: 10.1016/j.neuron.2017.10.034
Sandrine Lefort , Matthias H. Tschöp , Cristina García-Cáceres

Unraveling the brain control of metabolism may generate opportunities to discover novel precision medicines for obesity and diabetes. In this issue of Neuron, Liu et al. (2017) identify a novel glucagon-like peptide (GLP)-1 receptor-dependent signaling process that exerts anorexigenic action via the regulation of AMPA receptor subunit composition in the hypothalamus.

中文翻译:

大脑中GLP-1动作的突触基础。

放松大脑对新陈代谢的控制,可能会为发现肥胖症和糖尿病的新型精密药物提供机会。在《神经元》杂志上,Liu等人。(2017)确定了一种新型的胰高血糖素样肽(GLP)-1受体依赖性信号传导过程,该过程通过调节下丘脑中的AMPA受体亚基组成发挥镇痛作用。
更新日期:2017-11-16
down
wechat
bug