Benzannulated Re(I)–NHC complexes: synthesis, photophysical properties and antimicrobial activity,Dalton Transactions

当前位置： X-MOL 学术 › Dalton Trans. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Benzannulated Re(I)–NHC complexes: synthesis, photophysical properties and antimicrobial activity
Dalton Transactions ( IF 3.5 ) Pub Date : 2017-10-25 00:00:00 , DOI: 10.1039/c7dt02874a
Daniel Siegmund _{1,

2,

3,

4,

5} , Nicole Lorenz _{1,

2,

3,

4,

5} , Yvonne Gothe _{1,

2,

3,

4,

5} , Christian Spies _{3,

4,

5,

6,

7} , Bastian Geissler _{3,

4,

5,

6,

7} , Pascal Prochnow _{4,

7,

8,

9,

10} , Patrick Nuernberger _{3,

4,

5,

6,

7} , Julia E. Bandow _{4,

7,

8,

9,

10} , Nils Metzler-Nolte _{1,

2,

3,

4,

5}

Affiliation

A series of novel Re(I)(CO)₃–NHC complexes bearing unsubstituted benzimidazol-2-ylidene ligands as well as a variety of bisimine ligands has been prepared and comprehensively characterised. The complexes were found to exhibit potent antimicrobial activity on Gram-positive bacterial strains in the low micromolar concentration range, rendering these compounds interesting lead structures for the development of novel metal-based antibiotic agents. Further, the complexes exhibit pronounced luminescence with large Stokes shifts in acetonitrile and water at ambient temperature. The photophysical properties including luminescence lifetimes and quantum yields are consistent with emission from ³MLCT (d(Re) → π*(bisimine)) states.

中文翻译：

苯甲酰化的Re（I）-NHC配合物：合成，光物理性质和抗菌活性

制备了一系列具有未取代的苯并咪唑-2-亚基配体以及多种双亚胺配体的新颖的Re（I）（CO）₃ -NHC配合物，并对其进行了全面表征。发现该复合物在低微摩尔浓度范围内对革兰氏阳性细菌菌株表现出有效的抗菌活性，使这些化合物成为开发新型基于金属的抗生素试剂的引人关注的先导结构。此外，该复合物在环境温度下在乙腈和水中显示出明显的发光，并具有大的斯托克斯位移。包括发光寿命和量子产率的光物理性质与来自³ MLCT（d（Re）→π*（bisimine））状态的发射一致。

更新日期：2017-11-15

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11