A biorefinery strategy for the coproduction of ethanol and 1,5-pentanediol (1,5-PDO), which can be used as polyester and polyurethane component, from lignocellulosic biomass is proposed. This strategy integrates biomass fractionation with simultaneous conversion of hemicellulose and cellulose constituents into 1,5-PDO and ethanol, respectively. An experimentally-based process model is developed to determine the economic potential of the integrated strategy. The coproduction strategy becomes competitive with the ethanol-only strategy when 1,5-PDO can be sold at $1140/ton, which is well below the market price of 1,5-PDO. The most important process parameters include biomass loading for biomass fractionation, enzyme loading for enzymatic hydrolysis and fermentation, and overall achievable yields from C5 sugars to 1,5-PDO.

提出了从木质纤维素生物质联产乙醇和1,5-戊二醇（1,5-PDO）的生物精炼策略，该乙醇和1,5-戊二醇可用作聚酯和聚氨酯组分。该策略整合了生物质分馏功能，同时将半纤维素和纤维素成分同时分别转化为1,5-PDO和乙醇。开发了基于实验的过程模型，以确定集成策略的经济潜力。当1,5-PDO的销售价格为$ 1140 /吨，远远低于1,5-PDO的市场价格时，联合生产策略与仅乙醇的策略竞争激烈。最重要的工艺参数包括用于生物质分馏的生物量负载，用于酶促水解和发酵的酶负载以及从C5糖到1,5-PDO的总可实现产量。