Enhancing the precision of genetic lineage tracing using dual recombinases

Enhancing the precision of genetic lineage tracing using dual recombinases, Published online: 13 November 2017; doi:10.1038/nm.4437

NatureArticleSnippet(type=short-summary, markup=

Genetic cell-lineage tracing studies in mice are crucial for delineating the contribution of stem and progenitor cells to different cell types, both in disease states and after regenerative therapy. He et al. have developed new genetic lineage-tracing systems that provide more definitive results than the commonly used Cre-based system and show that this new technology can resolve current controversies in the field, as demonstrated by lineage-tracing studies in the heart and liver.

, isJats=true)

中文翻译：

---

使用双重重组酶提高遗传谱系追踪的精度

使用双重重组酶提高遗传谱系追踪的精度

使用双重重组酶提高遗传谱系追踪的准确性，在线发布：2017年11月13日；doi：10.1038 / nm.4437

NatureArticleSnippet（type = short-summary，markup =

小鼠中的遗传细胞谱系追踪研究对于描述干细胞和祖细胞在疾病状态和再生治疗后对不同细胞类型的贡献至关重要。他等。 已经开发了新的遗传谱系追踪系统，比常用的基于Cre的系统提供了更确定的结果，并且表明这种新技术可以解决该领域当前的争议，这在心脏和肝脏的谱系追踪研究中得到了证明。

，isJats = true）