当前位置: X-MOL 学术Nat. Chem. Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Nonimmune cells equipped with T-cell-receptor-like signaling for cancer cell ablation
Nature Chemical Biology ( IF 12.9 ) Pub Date :  , DOI: 10.1038/nchembio.2498
Ryosuke Kojima , Leo Scheller , Martin Fussenegger

Nonimmune cells equipped with T-cell-receptor-like signaling for cancer cell ablation

Nonimmune cells equipped with T-cell-receptor-like signaling for cancer cell ablation, Published online: 13 November 2017; doi:10.1038/nchembio.2498

NatureArticleSnippet(type=short-summary, markup=

Engineering of nonimmune cells with a cell-contact sensor and antigen recognition domains enables cell-contact-dependent sensor cell signaling and effector molecule production directed to attack target cells, providing an alternative strategy to chimeric antigen receptor T-cell (CAR-T) technology.

, isJats=true)


中文翻译:

配备T细胞受体样信号传导的非免疫细胞可用于癌细胞消融

配备T细胞受体样信号传导的非免疫细胞可用于癌细胞消融

配备T细胞受体样信号传导的非免疫细胞用于癌细胞消融,在线发布:2017年11月13日; doi:10.1038 / nchembio.2498

NatureArticleSnippet(type = short-summary,markup =

利用细胞接触传感器和抗原识别结构域对非免疫细胞进行工程改造,可以使依赖细胞接触的传感器细胞信号传导和效应分子产生,直接攻击靶细胞,从而为嵌合抗原受体T细胞(CAR-T)技术提供了另一种策略。

,isJats = true)
更新日期:2017-11-13
down
wechat
bug