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Biocatalytic site- and enantioselective oxidative dearomatization of phenols
Nature Chemistry ( IF 21.8 ) Pub Date : 2017-11-13 , DOI: 10.1038/nchem.2879
Summer A Baker Dockrey 1, 2 , April L Lukowski 2, 3 , Marc R Becker 1 , Alison R H Narayan 1, 2, 3
Affiliation  

Biocatalytic site- and enantioselective oxidative dearomatization of phenols

Biocatalytic site- and enantioselective oxidative dearomatization of phenols, Published online: 13 November 2017; doi:10.1038/nchem.2879

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Within natural product biosynthetic pathways, nature has evolved highly selective catalysts capable of complexity generating reactions. Leveraging these tools, a suite of catalysts with complementary site- and stereoselectivity have been applied to the oxidative dearomatization of phenolic compounds, enabling one-pot transformations of phenols into various natural products.

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中文翻译:

酚类的生物催化位点和对映选择性氧化脱芳构化

酚类的生物催化位点和对映选择性氧化脱芳构化

苯酚的生物催化位点和对映选择性氧化脱芳构化,在线发布:2017 年 11 月 13 日;doi:10.1038/nchem.2879

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在天然产物生物合成途径中,大自然已经进化出能够产生复杂反应的高选择性催化剂。利用这些工具,一套具有互补位点和立体选择性的催化剂已应用于酚类化合物的氧化脱芳构化,使酚类一锅法转化为各种天然产物。

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更新日期:2017-11-13
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