The ability to simultaneously monitor multiple analytes in, for example, a single microplate well, is important for both basic research and clinical applications. In particular, for disease diagnosis there is a growing awareness that determination of a single disease biomarker is insufficient to pathologically confirm a disease state. Consequently, much recent literature has been directed towards the development of multiplexed photoluminescent sensors which can simultaneously detect multiple and diverse biomarkers that exist in a homogenous solution or a single cell, accelerating the progress towards precise disease diagnosis. This tutorial review highlights a selection of recent contributions towards this emerging interdisciplinary field that incorporates chemistry, chemical biology, materials sciences and medical sciences.

中文翻译：

---

多重光致发光传感器：改善疾病诊断

同时监视例如单个微孔板孔中的多种分析物的能力对于基础研究和临床应用都是重要的。特别地，对于疾病诊断，人们越来越认识到，确定单一疾病生物标志物不足以在病理学上确认疾病状态。因此，许多最新的文献已指向开发可以同时检测存在于同质溶液或单个细胞中的多种多样的生物标记物的多重光致发光传感器，从而加速了精确疾病诊断的进程。本教程的回顾重点介绍了在这个新兴的跨学科领域中的最新贡献，该领域将化学，化学生物学，材料科学和医学科学融合在一起。