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Emerging biosensor platforms for the assessment of water-borne pathogens
Analyst ( IF 3.6 ) Pub Date : 2017-11-13 00:00:00 , DOI: 10.1039/c7an00983f Nishant Kumar 1, 2, 3, 4, 5 , Yuan Hu 6, 7, 8, 9 , Suman Singh 1, 2, 3, 4, 5 , Boris Mizaikoff 6, 7, 8, 9
Analyst ( IF 3.6 ) Pub Date : 2017-11-13 00:00:00 , DOI: 10.1039/c7an00983f Nishant Kumar 1, 2, 3, 4, 5 , Yuan Hu 6, 7, 8, 9 , Suman Singh 1, 2, 3, 4, 5 , Boris Mizaikoff 6, 7, 8, 9
Affiliation
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Pathogens are key contaminants in water that are responsible for the generation of various water-borne diseases, and include viruses, fungi, bacteria, and protozoan parasites. The pathogenic effects of these species in water depend on their shape, size, composition, and structure. The resulting water-borne diseases are a serious threat to the environment, including to humans and animals, and are directly responsible for environmental deterioration and pollution. The potential presence of these pathogens requires sensitive, powerful, efficient, and ideally real-time monitoring methods for their reproducible quantification. Conventional methods for pathogen detection mainly rely on time-consuming enrichment steps followed by biochemical identification strategies, which require assay times ranging from 24 h to up to a week. However, in recent years, significant efforts have been made towards the development of biosensing technologies enabling rapid and close-to-real-time detection of water-borne pathogens. This review summarizes recent developments in biosensors and sensing systems based on a variety of transducer technologies for water-quality monitoring, with specific focus on rapid pathogen detection.
中文翻译：
新兴的生物传感器平台，用于评估水生病原体
病原体是水中的关键污染物，可导致各种水传播疾病的产生，包括病毒，真菌，细菌和原生动物寄生虫。这些物种在水中的致病作用取决于它们的形状，大小，组成和结构。由此产生的水传播疾病严重危害环境，包括对人类和动物的环境，直接导致环境恶化和污染。这些病原体的潜在存在需要灵敏，强大，高效且理想的实时监测方法以实现可重复的定量。常规的病原体检测方法主要依靠费时的富集步骤以及随后的生化识别策略，这需要24小时至一周的测定时间。但是，近年来 为开发能够快速，实时地检测水生病原体的生物传感技术，已经做出了巨大的努力。这篇综述总结了基于多种用于水质监测的换能器技术的生物传感器和传感系统的最新发展，特别侧重于病原体的快速检测。
更新日期：2017-11-13
中文翻译：
新兴的生物传感器平台，用于评估水生病原体
病原体是水中的关键污染物，可导致各种水传播疾病的产生，包括病毒，真菌，细菌和原生动物寄生虫。这些物种在水中的致病作用取决于它们的形状，大小，组成和结构。由此产生的水传播疾病严重危害环境，包括对人类和动物的环境，直接导致环境恶化和污染。这些病原体的潜在存在需要灵敏，强大，高效且理想的实时监测方法以实现可重复的定量。常规的病原体检测方法主要依靠费时的富集步骤以及随后的生化识别策略，这需要24小时至一周的测定时间。但是，近年来 为开发能够快速，实时地检测水生病原体的生物传感技术，已经做出了巨大的努力。这篇综述总结了基于多种用于水质监测的换能器技术的生物传感器和传感系统的最新发展，特别侧重于病原体的快速检测。
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