Developing simple and selective methods for formaldehyde (FA) detection are of great interest, because FA is not only an environmental pollutant, but also an endogenous bioactive molecule. Herein, a new ratiometric fluorescent probe (HBT-FA) based on aza-Cope reaction was designed and synthesized, which showed high selectivity and ratiometric fluorescence response to FA. Furthermore, the probe could detect FA in various medium, such as aqueous solution, serum and air.

中文翻译：

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使用aza-cope反应的水溶液，血清和空气中甲醛的比例荧光探针

由于甲醛不仅是一种环境污染物，而且还是一种内源性生物活性分子，因此开发用于甲醛（FA）检测的简单而选择性的方法引起了人们的极大兴趣。本文设计并合成了一种基于aza-Cope反应的新型比例荧光探针（HBT-FA），该探针具有较高的选择性和对FA的比例荧光响应。此外，该探针可以检测各种介质（如水溶液，血清和空气）中的FA。